Xifaxan prices from $416.75. Compare mail-order and cash prices at 60,000+ US pharmacies with a free Rx.com coupon — no insurance needed. Xifaxan is a rifamycin which works by killing bacteria that causes infection. The most common form of Xifaxan is a 550mg tablet. It is also available as a 200mg tablet. There are currently no generic alternatives for Xifaxan. It is covered by some Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. Compare generic Xifaxan (rifaximin) prices from accredited international online pharmacies, U.S. mail-order pharmacies, and discount coupon programs. The lowest available price for generic Xifaxan (rifaximin) 550 mg is $0.61 per tablet for 200 tablets at PharmacyChecker-accredited online pharmacies. Get the facts on cost and Xifaxan, how the generic compares with the brand name, what financial assistance may be available, and more. Prices Coupons Patient assistance Xifaxan (rifaximin) is a member of the miscellaneous antibiotics drug class and is commonly used for Diarrhea, Hepatic Encephalopathy, Irritable Bowel Syndrome, and others. The cost for Xifaxan 550 mg oral tablet is around $4,339 for a supply of 60 tablets, depending on the pharmacy you visit. Get the best price on Xifaxan at pharmacies near you with SingleCare. Save up to 80% with our Xifaxan coupons – with or without insurance! Transfer your prescription for XIFAXAN 550 MG TAB on Amazon Pharmacy. FREE SHIPPING for Prime members. How much does Xifaxan cost? The list price of Xifaxan (rifaximin) varies widely depending on your insurance, pharmacy and dosage. Brand-name digestive health drugs are often expensive without coverage, which is why most people use insurance, manufacturer copay cards or pharmacy discount cards to lower the price. Is there a generic version of … The total cost of treatment without insurance could range from $421 (three days) to thousands of dollars (for longer treatments). Generic Xifaxan (rifaximin) is not yet available in the United States. A manufacturer's savings card or patient assistance program may help lower the cost of Xifaxan for eligible patients. How much does Xifaxan cost without insurance? The lowest listed cash price we found for Xifaxan 550 mg (60 ct) is $3839.09 at BetterBuy Rx, based on 1 pharmacy listing checked October 19, 2026. By choosing generic Rifaximin, patients can save over 90% compared to the retail price of Xifaxan. This makes it a highly cost-effective alternative for those requiring long-term treatment or repeated courses of the medication. Frequently Asked Questions about Xifaxan 1. Is Xifaxan covered by insurance? Yes, Xifaxan is covered by most health insurance plans, including Medicare and Medicaid … Xifaxan is a prescription drug used to treat some types of diarrhea and certain other conditions. Learn about the drug's cost, how to find savings, and more. Xifaxan (rifaximin) Savings – ordering the generic from abroad With Xifaxan projected to enjoy patent protection until 2029, cost relief through generic competition isn't exactly around the corner domestically. However, the generic is available to order online from pharmacies located overseas, specifically in India. How much would Xifaxan cost without insurance? Without insurance, a 30-day supply (90 tablets) of Xifaxan 550mg typically costs $5,000-$5,300 at U.S. pharmacies. Xifaxan in 2026 too expensive? Find manufacturer coupons, pharmacy discounts, generic options, and the best prices at pharmacies near you on Medfinder. Learn about Xifaxan (rifaximin) usage and dosing. Read the latest news and reviews about the drug as well as potential side effects and popular alternatives. Xifaxan costs about $461 for six tablets. Learn how the Xifaxan coupon, Xifaxan savings card, and other tools can help you save. The Xifaxan cost in the United States is often high, with many patients paying thousands for a short course. Understanding why it costs so much and what legal savings options exist can help patients and providers plan smarter treatment decisions. Research shows that the average cost of rifaximin for IBS-D is $1,250.76 for a two-week course with insurance, and the total cost can approach $3,000 … Find the lowest prices for Xifaxan at pharmacies near you. Get free RxSaver coupons and save up to 80% on your prescription. With no generic version available in the US, Xifaxan can be very expensive. Typically, generic drugs cost less than brand-name drugs as multiple pharmaceutical manufacturers sell the medication at competitive prices. Xifaxan cost runs $2,350-$3,950 for 60 tablets at U.S. retail in 2026. See real prices by condition, what the new generic means, and how to pay less. Xifaxan (generic name rifaximin) is an antibiotic primarily used for treating irritable bowel syndrome (IBS), travelers' diarrhea, and hepatic encephalopathy. It's proven to be a preferred option for many, thanks in large part to its localized mechanism of action in the gut and fewer systemic side effects compared to other antibiotics. However, Xifaxan costs can be prohibitive for some … Medicare coverage and pricing details for Xifaxan. Learn more about Medicare prescription drug plans and savings with GoodRx. Generic medications may be manufactured by different companies. This means some generics vary in size, color, and shape. But the active ingredients are always the same. Amazon Pharmacy uses different manufacturers to ensure medication supply and offer low prices for our customers. Therefore, people usually must pay out-of-pocket. Xifaxan and its generic can be purchased at a lower cost from pharmacies in Canada and other countries. People can easily save money on Xifaxan 550 mg by comparing Xifaxan prices at Canadian and international online pharmacies. Xifaxan sold in the U.S. is manufactured in Canada. Learn more about Xifaxan pricing, uses, and interactions. WellRx helps you find the cheapest pharmacy deals and drug savings. Save on Rifaximin in 2026: compare pharmacy prices, find coupons, and discover discount programs. Medfinder helps you find the lowest price near you. XIFAXAN (rifaximin) is an antibiotic used to treat hepatic encephalopathy (HE) and traveler's diarrhea. Its market trajectory is influenced by patent expiries, generic competition, and evolving treatment guidelines. What is the Current Market Status of XIFAXAN? XIFAXAN's primary indication is for the reduction of risk of overt hepatic encephalopathy recurrence in patients 18 years of age or … Xifaxan Xifaxan is prescribed to treat certain types of diarrhea and to lower the risk of a brain condition in adults with severe liver disease. It's a brand-name drug, available as the generic medication rifaximin. It comes as an oral tablet. The cost with or without insurance can depend on several factors. It might be lowered by using a coupon. Xifaxan is a brand-name drug that treats conditions like IBS-D and traveler's diarrhea. Without insurance, it costs about $2,000 per month, but no generic is available. Most health insurance plans, including Medicare Part D and Medicaid, cover Xifaxan. Restrictions such as prior authorization, quantity limits, and high out-of-pocket costs may … Compare the cost of prescription and generic Rifamycins medications. See information about popular Rifamycins, including the conditions they treat and alternatives available with or without insurance. Generic medications may be manufactured by different companies. This means some generics vary in size, color, and shape. But the active ingredients are always the same. Amazon Pharmacy uses different manufacturers to ensure medication supply and offer low prices for our customers. Many Americans choose to buy generic rifaximin from Canada because it is significantly cheaper than brand-name Xifaxan sold at U.S. retail pharmacies. With a valid prescription, Americans can order generic rifaximin from Canadian pharmacies and often pay a much lower price per tablet. Xifaxan vs rifaximin generic cost (550 mg) Generic vs. Brand Name Xifaxan is available as a brand name and a generic option. The generic version, rifaximin, often comes at a lower cost, making it an attractive option for patients looking to save money while still getting the required medication. Cost Breakdown of Xifaxan The cost of Xifaxan can be a concern for many patients. Treatment of irritable bowel syndrome with diarrhea (IBS-D). To lower the risk of hepatic encephalopathy, a brain condition caused by severe liver disease. Compare Xifaxan prices and find coupons that could save you up to 80% instantly at pharmacies near you such as CVS, Walgreens, Walmart, and many more. Why does Xifaxan® cost so much? The branded version commands premium pricing based on development investments and robust patent protection extending through 2029. Pharmaceutical companies justify high prices citing research costs for multiple indication approvals. Due to lack of US generic competition, pricing stays steep even for insured … Wondering how much does Xifaxan usually cost? This guide breaks down pricing without insurance, offers cost-saving tips, and explores patient assistance programs. The cost of Xifaxan depends on strength, quantity, brand versus generic, and where you purchase it. In the United States, brand-name Xifaxan can be extremely expensive at retail pharmacies, especially the 550 mg strength. How much does Xifaxan cost with The Rx Advocates? With The Rx Advocates, patients pay a fixed monthly service fee, which depends on the number of medications covered. 1 Medication (Xifaxan only) – $80 per month 2 Medications (Xifaxan + 1 other) – $90 per month 3 Medications (Xifaxan + 2 others) – $100 per month 4+ Medications – $110 per …